Biblography

General inflammasome information

Taming the inflammasome.” Levy M, Thaiss CA, Elinav E. Nature Medicine. 2015 Mar;21(3):213-5. DOI: 10.1038/nm.3808

Inflammasome inhibition: putting out the fire.” Netea MG, Joosten LA. Cell Metab. 2015 Apr 7;21(4):513-4. DOI: 10.1016/j.cmet.2015.03.012

 

Publications involving Inflazome founders

"IL-1β is an innate immune sensor of microbial proteolysis", Christopher N. LaRock, Jordan Todd, Doris L. LaRock, Joshua Olson, Avril A. Robertson, Matthew A. Cooper, Hal M. Hoffman, Victor Nizet, Science Immunology, 2016, 1 (2), pp.eaah3539,  DOI:10.1126/sciimmunol.aah3539

"NLRP3 inflammasome-mediated, IL-1β-dependent inflammatory responses drive steroid-resistant asthma", Jay Horvat, Richard Kim, James Pinkerton, Aam-Tawiah Essilfie, Avril Robertson, Katherine Baines, Jemma Mayall, Malcolm Starkey, Peter Wark, Peter Gibson, Luke O'Neill, Matthew A. Cooper, Philip Hansbro, European Respiratory Journal, 2016, 48. DOI: 10.1183/13993003.congress-2016.PA564

 “K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria”, Christina J. Groß, Ritu Mishra, Katharina S. Schneider, Guillaume Me´dard, Jennifer Wettmarshausen, Daniela C. Dittlein, Hexin Shi, Oliver Gorka, Paul-Albert Koenig,Stephan Fromm, Giovanni Magnani, Tamara Cikovi, Lara Hartjes, Joachim Smollich, Avril A.B. Robertson, Matthew A. Cooper, Marc Schmidt-Supprian, Michael Schuster, Kate Schroder, Petr Broz, Claudia Traidl-Hoffmann, Bruce Beutler, Bernhard Kuster, Jurgen Ruland, Sabine Schneider, Fabiana Perocchi, and Olaf Groß,Immunity, 2016, 45 (4), DOI: 10.1016/j.immuni.2016.08.010

“Role of the NLRP3 inflammasome in a model of acute burn-induced pain”, Jennifer Deuis,, Kathleen Yin, Matthew Cooper, Kate Schroder, Irina Vetter, BURNS, 2016DOI: 10.1016/j.burns.2016.09.001

“T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells”, Giuseppina Arbore, Erin E West, Avril A Robertson, Andreas Klos, Trent Woodruff, Luke A O'Neill, Alan Sher, Warren Leonard, Pete Monk, Matthew A Cooper, Andrew Cope, Katrin Mayer-Barber, Helen J Lachmann, Claudia Kemper, Science, 2016, 352 (6292), DOI: 10.1126/science.aad1210 

“Human Monocytes Engage an Alternative Inflammasome Pathway”, Moritz M. Gaidt, Thomas S. Ebert, Dhruv Chauhan, Tobias Schmidt, Jonathan L. Schmid-Burgk, Francesca Rapino, Avril A. B. Robertson, Matthew A. Cooper and Veit Hornung; Immunity, 2016, DOI: 10.1016/j.immuni.2016.01.012

“The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction“, European Heart Journal, 2016, DOI: 10.1093/eurheartj/ehw247

“Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition“, Anita Pinar, Jennifer K Dowling, Julie L McAuley, Avril AB Robertson, Eicke Latz, Grant R Drummond, Matthew A Cooper, Michelle D Tate and Ashley Mansell, Scientific Reports, 2016, 6: 27912, DOI: 10.1038/srep27912

“A small molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases,” R.C. Coll, A.A.B. Robertson, J.J. Chae, S.C.. Higgins, R. Muñoz-Planillo, M.C.. Inserra, I. Vetter, L.S.. Dungan, B.G.. Monks, A. Stutz, D.E. Croker, M.S. Butler, M. Haneklaus, C.E. Sutton, G. Núñez, E. Latz, D.L. Kastner, K.H.G. Mills, S.L. Masters, K. Schroder, MA Cooper, L.A.J. O’Neill, Nature Medicine, 2015, 21, 248-255, DOI: 10.1038/NM.3806

“Inflammasomes in COPD and neutrophilic asthma”, Richard Y Kim, James W Pinkerton, Peter G Gibson, Matthew A. Cooper, Jay C Horvat, Philip M Hansbro, Thorax, 2015, 70 (12), 1199-1201, DOI: 10.1136/thoraxjnl-2014-206736

“NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5”, Paul J. Baker, Dave Boucher, Damien Bierschenk, Christina Tebartz, Paul G. Whitney, Damian B. D'Silva, Maria C. Tanzer, Mercedes Monteleone, Avril A. B. Robertson, Matthew A. Cooper, Silvia Alvarez-Diaz, Marco J. Herold, Sammy Bedoui, Kate Schroder and Seth L. Masters, 2015, European Journal of Immunology, 45 (10), 2918 – 2926, DOI: 10.1002/eji.201545655

“Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice”, S.M. Krishnan, J.K. Dowling, Y.H. Ling, H. Diep, C.T. Chan, D. Ferens, M.M. Kett, A. Pinar, C.S. Samuel, A. Vinh, T.V. Arumugam, T.D. Hewitson, B.K. Kemp-Harper, A.A.B. Roberston, M.A. Cooper, E. Latz, A. Mansell, C.G. Sobey, G.R. Drummond. British J. Pharmacol., 2015, 173 (4), 752 – 765, DOI: 10.1111/bph.13230

“Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli”, Kolja Schaale, Kate M. Peters, Anna K. Fritzsche, Minh-Duy Phan, Makrina Totsika, Avril A.B. Robertson, Katie B. Nichols, Matthew A. Cooper, Glen C. Ulett, Katryn J. Stacey, Kate Schroder, Mark A. Schembri, Matthew J Sweet. Mucosal Immunology, 2015, 9 (1), 124-136, DOI: 10.1038/mi.2015.44